TRACHEOSTOMY AMONG CHILDREN ADMITTED IN THE PEDIATRIC INTENSIVE CARE UNIT OF A TERTIARY CARE CENTRE


Candidate genes involved in the biosynthesis of triterpenoid saponins in Platycodon grandiflorum identified by transcriptome analysis

Background: Platycodon grandiflorum is the only species in the genus Platycodon of the family Campanulaceae, which has been traditionally used as a medicinal plant for its lung-heat-clearing, antitussive, and expectorant properties in China, Japanese and Korean.Oleanane-type triterpenoid saponins were the main chemical components of P.grandiflorum

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Application of targeted high-throughput sequencing as a diagnostic tool for neonatal genetic metabolic diseases following tandem mass spectrometry screening

BackgroundTandem mass spectrometry (MS/MS) is a crucial technique for detecting inborn errors of metabolism (IEM) in newborns.However, the high false positive rate poses challenges in diagnosing specific types of diseases.Therefore, this Clutch Solenoid study aimed to evaluate the role of targeted next-generation sequencing (NGS) in the accurate di

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Modeling the influence of lime on the unconfined compressive strength of reconstituted graded soil using advanced machine learning approaches for subgrade and liner applications.

In the field of soil mechanics, especially in transportation and environmental geotechnics, the use of machine learning (ML) techniques has emerged as a powerful tool for predicting and understanding the compressive strength behavior of soils especially graded ones.This is to overcome the sophisticated equipment, laboratory space and cost needs uti

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